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Chicken and Spinach Casserole with Cream Cheese Recipe

Chicken and Spinach Casserole with Cream Cheese Recipe


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4.6 from 35 reviews

  • Total Time: 40 minutes
  • Yield: 8 1x

Description

Creamy chicken and spinach casserole delivers comfort straight from grandma’s kitchen. Melted cheese, tender chicken, and earthy spinach combine for a hearty meal that brings warmth to your dinner table.


Ingredients

Scale

Main Proteins:

  • 34 boneless, skinless chicken breasts (about 1 pound / 454 grams)
  • 8 ounces (226 grams) cream cheese, softened

Vegetables and Greens:

  • 4 cups fresh spinach

Cheese and Seasonings:

  • 2 cups shredded mozzarella cheese
  • 1 teaspoon garlic powder
  • Salt and pepper to taste

Other Ingredients:

  • 10.5 ounces (298 grams) can cream of mushroom soup

Instructions

  1. Preheat oven to 375°F (190°C) and lightly coat a 9×13 inch baking dish with cooking spray to prevent sticking.
  2. Slice chicken into uniform bite-sized pieces, then generously season with garlic powder, salt, and black pepper to enhance flavor profile.
  3. Heat olive oil in a skillet over medium temperature, gently sauté spinach until completely wilted and moisture has evaporated, approximately 3 minutes.
  4. In a mixing bowl, whisk softened cream cheese and cream of mushroom soup until completely smooth and free of lumps.
  5. Fold sautéed spinach and seasoned chicken pieces into the creamy mixture, ensuring all ingredients are evenly distributed and coated.
  6. Transfer the entire mixture into the prepared baking dish, spreading it evenly to create a consistent layer.
  7. Sprinkle shredded mozzarella cheese across the top, creating a complete coverage that will melt and develop a golden crust.
  8. Place in preheated oven and bake for 25-30 minutes, watching for a bubbling texture and golden-brown cheese topping.
  9. Remove from oven and let rest for 5 minutes to allow flavors to settle and casserole to set before serving.

Notes

  • Swap chicken for tofu or tempeh to create a vegetarian version that maintains the creamy, satisfying texture.
  • Use low-fat cream cheese and soup to reduce overall calorie content without sacrificing flavor.
  • Enhance nutrition by adding diced bell peppers or mushrooms for extra vegetables and depth of taste.
  • Freeze individual portions in airtight containers for quick weeknight meals that can be reheated in minutes.
  • Prep Time: 10 minutes
  • Cook Time: 30 minutes
  • Category: Dinner
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 8
  • Calories: 360
  • Sugar: 2 g
  • Sodium: 800 mg
  • Fat: 20 g
  • Saturated Fat: 10 g
  • Unsaturated Fat: 8 g
  • Trans Fat: 0 g
  • Carbohydrates: 8 g
  • Fiber: 1 g
  • Protein: 36 g
  • Cholesterol: 85 mg